SQSTM1 Antikörper (AA 232-356)
Kurzübersicht für SQSTM1 Antikörper (AA 232-356) (ABIN1846090)
Target
Alle SQSTM1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 232-356
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human SQSTM1 (AA: 232-356) expressed in E. coli.
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Isotyp
- IgG1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.0 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
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- SQSTM1 (Sequestosome 1 (SQSTM1))
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Andere Bezeichnung
- SQSTM1
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Hintergrund
- This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway.The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals.Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene.Mutations in this gene result in sporadic and familial Paget disease of bone.
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Molekulargewicht
- 47.7 kDa
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Pathways
- NF-kappaB Signalweg, Neurotrophin Signalübertragung, Autophagie
Target
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